HSD1590

Overview
Catalog #	bs-6846c-10mg-solid
Product Name	HSD1590
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 359.19 Formula: C20 H18 B N3 O3 CAS Number: 2379279-96-4 InChi Key: WTZMCUOBQPTERK-UHFFFAOYSA-N InChi: InChI=1S/C20H18BN3O3/c1-27-20-13(6-3-7-15(20)21(25)26)19-12-5-2-4-11(12)18-14-10-22-24-16(14)8-9-17(18)23-19/h3,6-10,25-26H,2,4-5H2,1H3,(H,22,24) Smiles: COC1C(=CC=CC=1B(O)O)C1=NC2C=CC3NN=CC=3C=2C2CCCC=21 Purity: 98.0 Solubility: DMSO: 100 mg/mL (278.40 mM; Need ultrasonic) Appearance: Solid Power. Shelf Life: 1.0 years
Description	HSD1590 is potent ROCK inhibitor, with IC50s of 1.22 and 0.51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity.