GO-6976

Overview
Catalog #	bs-6821c-10mg-solid
Product Name	GO-6976
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 378.43 Formula: C24 H18 N4 O CAS Number: 136194-77-9 InChi Key: VWVYILCFSYNJHF-UHFFFAOYSA-N InChi: InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29) Smiles: CN1C2C3=C(C4CNC(=O)C=4C=2C2C=CC=CC1=2)C1=CC=CC=C1N3CCC#N Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	GO-6976, also known as PD-406976, is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. GO-6976 blocked neurotrophin-induced signaling and autophosphorylation of neurotrophin-specific tyrosine kinase (Trk) receptors, either Trk B in cortical neurons or Trk A in GT1-1-trk9 cells.