Enzastaurin

Overview
Catalog #	bs-6790c-10mg-solid
Product Name	Enzastaurin
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 515.6 Formula: C32 H29 N5 O2 CAS Number: 170364-57-5 InChi Key: AXRCEOKUDYDWLF-UHFFFAOYSA-N InChi: InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39) Smiles: CN1C=C(C2=C(C3=CN(C4CCN(CC5C=CC=CN=5)CC4)C4=CC=CC=C34)C(=O)NC2=O)C2=CC=CC=C12 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	Enzastaurin, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.