BI-78D3

Overview
Catalog #	bs-6773c-10mg-solid
Product Name	BI-78D3
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 379.37 Formula: C13 H9 N5 O5 S2 CAS Number: 883065-90-5 InChi Key: QFRLDZGQEZCCJZ-UHFFFAOYSA-N InChi: InChI=1S/C13H9N5O5S2/c19-11-15-16-12(25-13-14-6-10(24-13)18(20)21)17(11)7-1-2-8-9(5-7)23-4-3-22-8/h1-2,5-6H,3-4H2,(H,15,19) Smiles: [O-][N+](=O)C1=CN=C(S1)SC1=NNC(=O)N1C1=CC2OCCOC=2C=C1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	BI-78D3, also known as JNK Inhibitor X, is a potent JNK inhibitor. BI-78D3 dose-dependently inhibits the phosphorylation of JNK substrates both in vitro and in cell. BI-78D3 not only blocks JNK dependent Con A-induced liver damage but also restores insulin sensitivity in mouse models of type 2 diabetes.