Lenvatinib Mesylate
Overview | |
Catalog # | bs-6720c-10mg-solid |
Product Name | Lenvatinib Mesylate |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 522.96 Formula: C22 H23 Cl N4 O7 S CAS Number: 857890-39-2 InChi Key: HWLFIUUAYLEFCT-UHFFFAOYSA-N InChi: InChI=1S/C21H19ClN4O4.CH4O3S/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11;1-5(2,3)4/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28);1H3,(H,2,3,4) Smiles: COC1C=C2N=CC=C(OC3=CC(Cl)=C(C=C3)NC(=O)NC3CC3)C2=CC=1C(N)=O.CS(O)(=O)=O Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years |
Description | Lenvatinib Mesylate, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR/FLK-1) tyrosine kinase with potential antineoplastic activity. E7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis. |