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KN-93 Phosphate

Overview
Catalog # bs-6714c-10mg-solid
Product Name KN-93 Phosphate
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 599.03

Formula: C26 H32 Cl N2 O8 P S

CAS Number: 1188890-41-6

InChi Key: NNKJTPOXLIILMB-IPZCTEOASA-N

InChi: InChI=1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+;

Smiles: CN(CC1C=CC=CC=1N(CCO)S(=O)(=O)C1C=CC(=CC=1)OC)C/C=C/C1C=CC(Cl)=CC=1.OP(O)(O)=O

Purity: 98.0

Solubility: DMSO : 100 mg/mL (166.94 mM; Need ultrasonic)

Appearance: Solid Power.

Shelf Life: 1.0 years
Description KN-93 Phosphate is a CaMKII inhibitor. KN-93 suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR. KN-93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer. KN-93 ameliorates levodopa-induced dyskinesia in a rat model of Parkinson's disease. KN-93 protects rat cerebral cortical neurons from N-methyl-D-aspartic acid-induced injury.