Verubecestat

Overview
Catalog #	bs-6661c-10mg-solid
Product Name	Verubecestat
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 409.41 Formula: C17 H17 F2 N5 O3 S CAS Number: 1286770-55-5 InChi Key: YHYKUSGACIYRML-KRWDZBQOSA-N InChi: InChI=1S/C17H17F2N5O3S/c1-17(9-28(26,27)24(2)16(20)23-17)12-7-11(4-5-13(12)19)22-15(25)14-6-3-10(18)8-21-14/h3-8H,9H2,1-2H3,(H2,20,23)(H,22,25)/t17-/m0/s1 Smiles: CN1C(N)=N[C@@](C)(CS1(=O)=O)C1C=C(C=CC=1F)NC(=O)C1C=CC(F)=CN=1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.