MGL-3196

Overview
Catalog #	bs-6626c-10mg-solid
Product Name	MGL-3196
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 435.22 Formula: C17 H12 Cl2 N6 O4 CAS Number: 920509-32-6 InChi Key: FDBYIYFVSAHJLY-UHFFFAOYSA-N InChi: InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(14)19)25-17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27,28) Smiles: CC(C)C1=CC(=NNC1=O)OC1C(Cl)=CC(=CC=1Cl)N1N=C(C#N)C(=O)NC1=O Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	MGL-3196, also known as Resmetirom, is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia. The beneficial effects of thyroid hormone (TH) on lipid levels are primarily due to its action at the thyroid hormone receptor β (THR-β) in the liver, while adverse effects, including cardiac effects, are mediated by thyroid hormone receptor α (THR-α).