R1664,PPAR-γ Modulator

Overview
Catalog #	bs-66048c-10mg-solid
Product Name	R1664,PPAR-γ Modulator
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 547.6 Formula: C33 H29 N3 O5 CAS Number: 1338259-05-4 InChi Key: IIJDFXNUWZTHIM-NRFANRHFSA-N InChi: InChI=1S/C33H29N3O5/c1-20-22(3)35(19-23-8-10-25(11-9-23)28-6-4-5-7-29(28)33(38)39)31-17-14-26(18-30(20)31)32(37)34-21(2)24-12-15-27(16-13-24)36(40)41/h4-18,21H,19H2,1-3H3,(H,34,37)(H,38,39)/t21-/m0/s1 Smiles: C[C@H](NC(=O)C1C=C2C(=CC=1)N(CC1C=CC(=CC=1)C1=CC=CC=C1C(O)=O)C(C)=C2C)C1C=CC(=CC=1)[N+]([O-])=O Purity: 98.0 Solubility: DMSO up to 25 mM Appearance: Solid Power. Shelf Life: 1.0 years
Description	SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPARγ agonist activity.