CZC24832

Overview
Catalog #	bs-6594c-10mg-solid
Product Name	CZC24832
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 364.4 Formula: C15 H17 F N6 O2 S CAS Number: 1159824-67-5 InChi Key: RXRZPHQBTHQXSV-UHFFFAOYSA-N InChi: InChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20) Smiles: CC(C)(C)NS(=O)(=O)C1C=NC=C(C=1)C1C=C(F)C2=NC(N)=NN2C=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years
Description	CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.