CW069

Overview
Catalog #	bs-6570c-10mg-solid
Product Name	CW069
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 500.33 Formula: C23 H21 I N2 O3 CAS Number: 1594094-64-0 InChi Key: IRDIXDXDSUBHIU-NRFANRHFSA-N InChi: InChI=1S/C23H21IN2O3/c24-18-11-12-20(19(14-18)23(28)29)26-22(27)21(13-16-7-3-1-4-8-16)25-15-17-9-5-2-6-10-17/h1-12,14,21,25H,13,15H2,(H,26,27)(H,28,29)/t21-/m0/s1 Smiles: OC(=O)C1C=C(I)C=CC=1NC(=O)[C@H](CC1C=CC=CC=1)NCC1C=CC=CC=1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years
Description	CW069 is an allosteric inhibitor of HSET. CW069 showed marked activity against HSET in vitro. The inhibitor induced multipolar mitoses only in cells containing supernumerary centrosomes. CW069 therefore constitutes a valuable tool for probing HSET function and, by reducing the growth of cells containing supernumerary centrosomes, paves the way for new cancer therapeutics.