R-(+)-ETOMOXIR

Overview
Catalog #	bs-6565c-10mg-solid
Product Name	R-(+)-ETOMOXIR
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 326.82 Formula: C17 H23 Cl O4 CAS Number: 124083-20-1 InChi Key: DZLOHEOHWICNIL-QGZVFWFLSA-N InChi: InChI=1S/C17H23ClO4/c1-2-20-16(19)17(13-22-17)11-5-3-4-6-12-21-15-9-7-14(18)8-10-15/h7-10H,2-6,11-13H2,1H3/t17-/m1/s1 Smiles: CCOC(=O)[C@@]1(CCCCCCOC2C=CC(Cl)=CC=2)CO1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years
Description	R-(+)-ETOMOXIR is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPARα.