ESI-09

Overview
Catalog #	bs-6558c-10mg-solid
Product Name	ESI-09
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 330.77 Formula: C16 H15 Cl N4 O2 CAS Number: 263707-16-0 InChi Key: DXEATJQGQHDURZ-DEDYPNTBSA-N InChi: InChI=1S/C16H15ClN4O2/c1-16(2,3)14-8-12(21-23-14)15(22)13(9-18)20-19-11-6-4-5-10(17)7-11/h4-8,19H,1-3H3/b20-13+ Smiles: CC(C)(C)C1=CC(=NO1)C(=O)/C(/C#N)=N/NC1=CC(Cl)=CC=C1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years
Description	ESI-09 is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC-mediated Rap1 activation and Akt phosphorylation, as well as EPAC-mediated insulin secretion in pancreatic β cells. EPAC1 plays an important role in pancreatic cancer cell migration and invasion, and thus represents a potential target for developing novel therapeutic strategies for pancreatic cancer.