GNE-617

Overview
Catalog #	bs-6546c-2mg-solid
Product Name	GNE-617
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 427.42 Formula: C21 H15 F2 N3 O3 S CAS Number: 1362154-70-8 InChi Key: XRDVXQQZLHVEQZ-UHFFFAOYSA-N InChi: InChI=1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27) Smiles: O=C(NCC1C=CC(=CC=1)S(=O)(=O)C1C=C(F)C=C(F)C=1)C1=CN2C=CN=C2C=C1 Purity: 98.0 Solubility: DMSO: 42 mg/mL(98.26 mM). Appearance: Solid Power Shelf Life: 1.0 years
Description	GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC50 value of 5nM. Prolonged inhibition of nicotinamide phosphoribosyltransferase (NAMPT) is a strategy for targeting cancer metabolism.