PD-166866

Overview
Catalog #	bs-6541c-2mg-solid
Product Name	PD-166866
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 396.44 Formula: C20 H24 N6 O3 CAS Number: 192705-79-6 InChi Key: NHJSWORVNIOXIT-UHFFFAOYSA-N InChi: InChI=1S/C20H24N6O3/c1-20(2,3)26-19(27)25-17-15(8-12-10-22-18(21)24-16(12)23-17)11-6-13(28-4)9-14(7-11)29-5/h6-10H,1-5H3,(H4,21,22,23,24,25,26,27) Smiles: CC(C)(C)NC(=O)NC1N=C2N=C(N)N=CC2=CC=1C1C=C(C=C(C=1)OC)OC Purity: 98.0 Solubility: DMSO: 14 mg/mLwarmed(35.31 mM). Appearance: Solid Power Shelf Life: 1.0 years
Description	PD-166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4. PD-166866 has clear antiproliferative effects.