Eg5 Inhibitor III
| Overview | |
| Catalog # | bs-6537c-2mg-solid |
| Product Name | Eg5 Inhibitor III |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 302.39 Formula: C16 H18 N2 O2 S CAS Number: 863774-58-7 InChi Key: RUOOPLOUUAYNPY-UHFFFAOYSA-N InChi: InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21) Smiles: CC1(C)CC2NC(=S)NC(C=2C(=O)C1)C1C=CC=C(O)C=1 Purity: 98.0 Solubility: DMSO : 100 mg/mL (330.70 mM; Need ultrasonic) Appearance: Solid Power Shelf Life: 1.0 years |
| Description | Eg5 Inhibitor III is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Eg5 Inhibitor III suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours. |
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