PMPA

Overview
Catalog #	bs-6520c-2mg-solid
Product Name	PMPA
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 226.12 Formula: C6 H11 O7 P CAS Number: 173039-10-6 InChi Key: ISEYJGQFXSTPMQ-UHFFFAOYSA-N InChi: InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13) Smiles: OC(=O)CCC(CP(O)(O)=O)C(O)=O Purity: 98.0 Solubility: H2O : ≥ 28 mg/mL (123.83 mM) Appearance: Solid Power Shelf Life: 1.0 years
Description	PMPA is a NAALADase inhibitor. PMPA increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice. Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. PMPA attenuates magnetic resonance BOLD signals in brain of anesthetized mice: evidence of a link between neuron NAAG release and hyperemia.