CPI-0610

Overview
Catalog #	bs-6503c-10mg-solid
Product Name	CPI-0610
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 365.81 Formula: C20 H16 Cl N3 O2 CAS Number: 1380087-89-7 InChi Key: GCWIQUVXWZWCLE-INIZCTEOSA-N InChi: InChI=1S/C20H16ClN3O2/c1-11-18-14-4-2-3-5-15(14)19(12-6-8-13(21)9-7-12)23-16(10-17(22)25)20(18)26-24-11/h2-9,16H,10H2,1H3,(H2,22,25)/t16-/m0/s1 Smiles: CC1=NOC2[C@H](CC(N)=O)N=C(C3C=CC=CC=3C=21)C1C=CC(Cl)=CC=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years
Description	CPI-0610, also known as Pelabresib, is a small molecule inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon administration, the BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth.