BPTES

Overview
Catalog #	bs-6502c-10mg-solid
Product Name	BPTES
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 524.68 Formula: C24 H24 N6 O2 S3 CAS Number: 314045-39-1 InChi Key: MDJIPXYRSZHCFS-UHFFFAOYSA-N InChi: InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-13-33-14-12-22-28-30-24(35-22)26-20(32)16-18-9-5-2-6-10-18/h1-10H,11-16H2,(H,25,29,31)(H,26,30,32) Smiles: O=C(CC1=CC=CC=C1)NC1=NN=C(CCSCCC2=NN=C(NC(=O)CC3=CC=CC=C3)S2)S1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years
Description	BPTES is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. BPTES has a K(i) of approx. 3 microM. BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex.