GTS-21 2HCl

Overview
Catalog #	bs-6493c-2mg-solid
Product Name	GTS-21 2HCl
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 381.3 Formula: C19 H22 Cl2 N2 O2 CAS Number: 156223-05-1 InChi Key: BXKYFUGAAFLYJL-BXGYHSFXSA-N InChi: InChI=1S/C19H20N2O2.2ClH/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16;;/h3,6-9,11-13H,4-5,10H2,1-2H3;2*1H/b15-11+;; Smiles: Cl.Cl.COC1C=C(C=CC=1/C=C1\CCCN=C\1C1C=NC=CC=1)OC Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years
Description	GTS-21 2HCl, also known as DMBX-A, is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the α4β2 and α7 subtypes, but activates only the α7 to any significant extent. Both GTS-21 itself and its demethylated active metabolite 4-OH-GTS-21 display nootropic and neuroprotective effects, and GTS-21 is being investigated for the treatment of Alzheimer's disease, nicotine dependence, and, most significantly, for schizophrenia.