PD158780

Overview
Catalog #	bs-6424c-10mg-solid
Product Name	PD158780
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 330.18 Formula: C14 H12 Br N5 CAS Number: 171179-06-9 InChi Key: KFHMLBXBRCITHF-UHFFFAOYSA-N InChi: InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20) Smiles: CNC1=CC2C(NC3=CC(Br)=CC=C3)=NC=NC=2C=N1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years
Description	PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50 0.08 nM), and other members of the erbB family, by competitive binding at the ATP site of these signal transduction enzymes.