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BS-181 HCl

Overview
Catalog # bs-6415c-10mg-solid
Product Name BS-181 HCl
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 416.99

Formula: C22 H33 Cl N6

CAS Number: 1397219-81-6

InChi Key: NVIJWMOQODWNFN-UHFFFAOYSA-N

InChi: InChI=1S/C22H32N6.ClH/c1-17(2)19-16-26-28-21(25-15-18-10-6-5-7-11-18)14-20(27-22(19)28)24-13-9-4-3-8-12-23;/h5-7,10-11,14,16-17,25H,3-4,8-9,12-13,15,23H2,1-2H3,(H,24,27);1H

Smiles: Cl.CC(C)C1C=NN2C(=CC(NCCCCCCN)=NC2=1)NCC1C=CC=CC=1

Purity: 98.0

Solubility: ≥ 20.85mg/mL in DMSO, ≥ 6.49 mg/mL in EtOH with ultrasonic

Appearance: Solid Power

Shelf Life: 1.0 years
Description BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.