GSK-3787
Overview | |
Catalog # | bs-6404c-2mg-solid |
Product Name | GSK-3787 |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 392.78 Formula: C15 H12 Cl F3 N2 O3 S CAS Number: 188591-46-0 InChi Key: JFUIMTGOQCQTPF-UHFFFAOYSA-N InChi: InChI=1S/C15H12ClF3N2O3S/c16-12-4-1-10(2-5-12)14(22)20-7-8-25(23,24)13-6-3-11(9-21-13)15(17,18)19/h1-6,9H,7-8H2,(H,20,22) Smiles: O=C(NCCS(=O)(=O)C1C=CC(=CN=1)C(F)(F)F)C1C=CC(Cl)=CC=1 Purity: 98.0 Solubility: soluble in DMSO, not soluble in water. Appearance: Solid Power Shelf Life: 1.0 years |
Description | GSK-3787 is a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist with good pharmacokinetic properties. GSK3787 can antagonize PPARbeta/delta in vivo, thus providing a new strategy to delineate the functional role of a receptor with great potential as a therapeutic target for the treatment and prevention of disease. |