CIQ
Overview | |
Catalog # | bs-6401c-2mg-solid |
Product Name | CIQ |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 467.94 Formula: C26 H26 Cl N O5 CAS Number: 486427-17-2 InChi Key: VYMILMYEENZHAR-UHFFFAOYSA-N InChi: InChI=1S/C26H26ClNO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3 Smiles: COC1C=CC(=CC=1)OCC1C2=CC(OC)=C(C=C2CCN1C(=O)C1=CC(Cl)=CC=C1)OC Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years |
Description | CIQ is a GluN2C/GluN2D subunit-selective NMDA receptor potentiator, which reverses MK-801-induced impairment in prepulse inhibition and working memory in Y-maze test in mice. The facilitation of GluN2C/GluN2D-containing receptors may serve as an important therapeutic strategy for treating positive and cognitive symptoms in schizophrenia. |