PD0332991 HCl

Overview
Catalog #	bs-60429c-2mg-solid
Product Name	PD0332991 HCl
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 483.99 Formula: C24 H30 Cl N7 O2 CAS Number: 827022-32-2 InChi Key: STEQOHNDWONVIF-UHFFFAOYSA-N InChi: InChI=1S/C24H29N7O2.ClH/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32;/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29);1H Smiles: Cl.CC(=O)C1C(=O)N(C2CCCC2)C2N=C(NC3C=CC(=CN=3)N3CCNCC3)N=CC=2C=1C Purity: 98.0 Solubility: DMSO: 6 mg/mL (Need ultrasonic or warming); H2O: 4.9 mg/mL (Need ultrasonic or warming) Appearance: Solid Power Shelf Life: 1.0 years
Description	Palbociclib hydrochloride is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.