MSAB, β-catenin Inhibitor
| Overview | |
| Catalog # | bs-60316c-2-mg-solid |
| Product Name | MSAB, β-catenin Inhibitor |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 305.35 Formula: C15 H15 N O4 S CAS Number: 173436-66-3 InChi Key: CVKBYFCJQSPBOI-UHFFFAOYSA-N InChi: InChI=1S/C15H15NO4S/c1-11-6-8-14(9-7-11)21(18,19)16-13-5-3-4-12(10-13)15(17)20-2/h3-10,16H,1-2H3 Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC1C=C(C=CC=1)C(=O)OC Purity: 98.0 Solubility: DMSO up to 100 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | MSAB is a potent and selective Wnt/β-catenin inhibitor identified using cell-based chemical screening. It binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models. |
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