ISX9, Neurogenic Modulator
| Overview | |
| Catalog # | bs-60274c-2-mg-solid |
| Product Name | ISX9, Neurogenic Modulator |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 234.27 Formula: C11 H10 N2 O2 S CAS Number: 832115-62-5 InChi Key: SYENTKHGMVKGAQ-UHFFFAOYSA-N InChi: InChI=1S/C11H10N2O2S/c14-11(12-7-3-4-7)8-6-9(15-13-8)10-2-1-5-16-10/h1-2,5-7H,3-4H2,(H,12,14) Smiles: O=C(NC1CC1)C1C=C(ON=1)C1=CC=CS1 Purity: 98.0 Solubility: DMSO up to 100 mM, EtOH up to 50 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | ISX9 is a neurogenic modulator. It mediates neuroD reporter gene induction via activation of Ca2+ influx, and increases expression of neurogenic differentiation 1 (NeuroD1) transcription factor. It induces neuronal differentiation in human cortical neuronal cells (HCN), adult mouse whole brain (MWB) and subventricular zone (SVZ) progenitors. ISX9 is also shown to induce cardiomyogenic differentiation of Notch-activated epicardium-derived cells in vitro. |
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