BAZ2-ICR --- BAZ2 Bromodomain Inhibitor
| Overview | |
| Catalog # | bs-60226c-2-mg-solid |
| Product Name | BAZ2-ICR --- BAZ2 Bromodomain Inhibitor |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 357.41 Formula: C20 H19 N7 CAS Number: 1665195-94-7 InChi Key: RRZVGDGTWNQAPW-UHFFFAOYSA-N InChi: InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3 Smiles: CN1C=C(C=N1)C1N=CN(CCC2C=NN(C)C=2)C=1C1=CC=C(C=C1)C#N Purity: 98.0 Solubility: DMSO up to 100 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | BAZ2-ICR is a potent and selective BAZ2 bromodomain inhibitor with Kd values of 109 and 170 nM for BAZ2A and BAZ2B, respectively. It exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains. It shows accelerated FRAP recovery at 1 ¦ÌM in the BAZ2A FRAP assay. |
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