| Overview |
| bs-5583R-PE-Cy5.5 |
| PRKCQ(Ser676) Polyclonal Antibody, PE-Cy5.5 Conjugated |
| WB |
| Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
| Specifications |
| PE-Cy5.5 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human PRKCQ around the phosphorylation site of Ser676 |
| Ser676 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5588 |
| Cytoplasm, Cell membrane |
| PRKCQphospho S676; PKCSer676; PKC thetaphospho S676; PKC 0; PRKCQ; PKC0; Prkcq; PRKCT; Protein kinase C theta; Protein kinase C theta type; Protein Kinase Ctheta; KPCT_HUMAN; nPKC theta; nPKC-theta; nPKCtheta. |
| This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. |
| Application Dilution |
| WB |
1:300-5000 |
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