| Overview |
| bs-5542R-APC-Cy7 |
| PAK1(Thr212) Polyclonal Antibody, APC-Cy7 Conjugated |
| IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Mouse, Rat |
| Dog, Rabbit |
| Specifications |
| APC-Cy7 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human PAK1 around the phosphorylation site of Thr212 |
| Thr212 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5058 |
| Cytoplasm, Cell membrane |
| PAK1Thr212; PAK1phospho T212; Alpha PAK; Alpha-PAK; MGC130000; MGC130001; p21 activated kinase 1; p21 protein Cdc42/Rac activated kinase 1; p21-activated kinase 1; p21/Cdc42/Rac1 activated kinase 1 yeast Ste20 related; p21/Cdc42/Rac1 activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 STE20 homolog, yeast; p65 PAK; p65-PAK; PAK alpha; PAK-1; Pak1; PAK1_HUMAN; Paka; PAKalpha; Protein kinase MUK2; Rac/p21-activated kinase; Serine/threonine-protein kinase PAK 1; STE20 homolog yeast; STE20 homolog yeast. |
| The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. |
| Application Dilution |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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