Overview |
bs-55057R |
DPYSL2 Polyclonal Antibody |
WB |
Human |
Specifications |
Unconjugated |
Rabbit |
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DPYSL2 (NP_001377.1). |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
1808 |
Q16555 |
Cytoplasm |
DPYSL2;CRMP-2;CRMP2;DHPRP2;DRP-2;DRP2;N2A3;ULIP-2;ULIP2 |
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Application Dilution |
WB |
1:300-5000 |