BAK1 Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-55017R |
Product Name | BAK1 Polyclonal Antibody |
Applications | WB, IHC |
Reactivity | Human, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | A synthetic peptide of human BAK1 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C for 12 months. |
Target | |
Gene ID | 578 |
Swiss Prot | Q16611 |
Subcellular location | Cytoplasm, Cell membrane |
Synonyms | BAK1;BAK;BAK-LIKE;BCL2L7 |
Background | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
Application Dilution | |
WB | 1:300-5000 |
IHC |