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MBP(Tyr203) Polyclonal Antibody, Cy5.5 Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
Overview
Catalog # bs-5475R-Cy5.5
Product Name MBP(Tyr203) Polyclonal Antibody, Cy5.5 Conjugated
Applications WB
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog
Specifications
Conjugation Cy5.5
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human MBP around the phosphorylation site of Tyr203
Modification Site Tyr203
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4155
Subcellular location Cytoplasm, Cell membrane
Synonyms MBPphospho Y203; Myelin basic protien; GDB; Golli MBP; Hemopoietic MBP; HMBPR; HUGO; MBP; MGC99675; MLD; Myelin A1 Protein; Myelin Deficient; Myelin Membrane Encephalitogenic Protein; SHI; Shiverer; SP.
Background Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
Application Dilution
WB 1:300-5000