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NADPH oxidase 4 Polyclonal Antibody, Cy5 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
Overview
Catalog # bs-4730R-Cy5
Product Name NADPH oxidase 4 Polyclonal Antibody, Cy5 Conjugated
Applications WB, FCM
Reactivity Human
Specifications
Conjugation Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human NOX4
Immunogen Range 201-300/578
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 50507
Swiss Prot Q9NPH5
Subcellular location Cell membrane
Synonyms Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; KOX 1; KOX; Kox-1; NADPH; NADPH oxidase 4; Nox4; NOX4_HUMAN; Renal NADPH-oxidase; RENOX.
Background Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
Application Dilution
WB 1:300-5000
FCM 1:20-100