Overview |
bs-2901R-PE-Cy3 |
RECK Polyclonal Antibody, PE-Cy3 Conjugated |
WB |
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit |
Specifications |
PE-Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human RECK |
801-900/971 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
8434 |
O95980 |
Cell membrane |
ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein; RECK |
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression. |
Application Dilution |
WB |
1:300-5000 |