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MGMT Polyclonal Antibody, AbBy Fluor® 555 Conjugated

Applications

  • WB

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-24479R-BF555
Product Name MGMT Polyclonal Antibody, AbBy Fluor® 555 Conjugated
Applications WB
Reactivity Rat
Predicted Reactivity Human, Mouse
Specifications
Conjugation AbBy Fluor® 555
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse MGMT
Immunogen Range 1-100/207
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 17314
Swiss Prot P26187
Subcellular location Nucleus
Synonyms 6 O methylguanine DNA methyltransferase; Agat; AGT; AI267024; EC 2.1.1.63; Methylated DNA protein cysteine methyltransferase; Methylguanine DNA methyltransferase; MGC107020; MGMT: O-6 methylguanine DNA methyltransferase; O 6 methylguanine DNA alkyltransferase; O 6 methylguanine DNA methyltransferase; O-6 methylguanine DNA alkyltransferase; O-6-methylguanine-DNA methyltransferase; O6 methylguanine DNA methyltransferase; MGMT_HUMAN.
Background Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Application Dilution
WB 1:300-5000