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NCR1 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-23550R-Biotin
Product Name NCR1 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Human, Mouse
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human NCR1
Immunogen Range 1-100/304
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID O76036
Swiss Prot 9437
Subcellular location Cell membrane
Synonyms Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1; NK-p46; NKp46; NK cell-activating receptor; Lymphocyte antigen 94 homolog; CD335; CD 335; LY94; NCTR1_HUMAN.
Background The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500