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Caldesmon (Ser789) Polyclonal Antibody, PE-Cy3 Conjugated

Applications

  • WB

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Horse
  • Rabbit
Overview
Catalog # bs-2082R-PE-Cy3
Product Name Caldesmon (Ser789) Polyclonal Antibody, PE-Cy3 Conjugated
Applications WB
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Cow, Horse, Rabbit
Specifications
Conjugation PE-Cy3
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser789
Modification Site Ser789
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 800
Subcellular location Cytoplasm
Synonyms Caldesmon S789; Caldesmon Ser789; p-Caldesmon S789; p-Caldesmon Ser789; p-Caldesmon Ser789; CAD; CALD 1; CALD1; CALD1_HUMAN; Caldesmon 1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; Caldesmon; Caldesmon1; CDM; H CAD; HCAD; L CAD; LCAD; MGC21352; NAG22.
Background This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008].
Application Dilution
WB 1:300-5000