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MITF Polyclonal Antibody, Cy3 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Mouse
  • Others

Predicted Reactivity

  • Human
  • Rat
  • Dog
  • Cow
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-1990R-Cy3
Product Name MITF Polyclonal Antibody, Cy3 Conjugated
Applications WB, IF(IHC-P)
Reactivity Mouse, Others
Predicted Reactivity Human, Rat, Dog, Cow, Horse, Chicken, Rabbit
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human MITF
Immunogen Range 351-450/526
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4286
Swiss Prot O75030
Subcellular location Nucleus
Synonyms MI; WS2; CMM8; WS2A; bHLHe32; Microphthalmia-associated transcription factor; Class E basic helix-loop-helix protein 32; MITF
Background Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200