New to Bioss? Enjoy 35% of your first order. Use code "FirstOrder35" - Offer valid for new U.S. Customers on direct orders only

CLEC16A Polyclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Cow
  • Pig
Overview
Catalog # bs-18539R-PE-Cy5
Product Name CLEC16A Polyclonal Antibody, PE-Cy5 Conjugated
Applications WB, FCM
Reactivity Human
Predicted Reactivity Mouse, Rat, Cow, Pig
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CLEC16A
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 23274
Swiss Prot Q2KHT3
Subcellular location Cytoplasm, Cell membrane
Synonyms Gop-1; KIAA0350; Protein CLEC16A; C-type lectin domain family 16 member A; CLEC16A
Background Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.
Application Dilution
WB 1:300-5000
FCM 1:20-100