| Overview |
| bs-12431R-PE |
| DOCK2 Polyclonal Antibody, PE Conjugated |
| WB |
| Human, Mouse, Rat, Dog, Cow, Sheep |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human DOCK2 |
| 451-550/1830 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1794 |
| Q92608 |
| Cell membrane |
| Dedicator of cytokinesis protein 2; DOCK2; KIAA0209 |
| Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
| Application Dilution |
| WB |
1:300-5000 |
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