| Overview |
| bs-12266R-Biotin |
| GGNBP1 Polyclonal Antibody, Biotin Conjugated |
| WB, ELISA, IHC-P, IHC-F |
| Human |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GGNBP1 |
| 25-109/109 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| Cytoplasm, Cell membrane |
| Gametogenetin-binding protein 1; GGNBP1; Putative gametogenetin-binding protein 1; GGNB1_HUMAN. |
| GGNBP1 is a 109 amino acid protein that is thought to be involved in spermatogenesis and interacts with gametogenetin. GGNBP1 localizes to cytoplasm, membrane and Golgi apparatus, and exits as two isoforms which are produced by alternative splicing events. The gene encoding GGNBP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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