| Overview |
| bs-11091r-pe-cy5-100ul |
| LSAMP Polyclonal Antibody, PE-Cy5 Conjugated |
| WB |
| Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit |
| Specifications |
| PE-Cy5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human LSAMP |
| 51-150/338 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| Cell membrane |
| IgLON family member 3; IGLON3; Lam; LAMP; Limbic system associated membrane protein; Limbic system associated membrane protein precursor; Limbic system-associated membrane protein; LSAMP; LSAMP_HUMAN. |
| LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons. It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules. LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor. It is a highly conserved protein between rodents and humans (99% sequence identity) and it is involved in the regulation of neurite outgrowth and mediation of proper circuit formation of limbic pathways. This suggests that LSAMP plays an important role in the development and function of the limbic system. In addition, LSAMP may function as a tumor suppressor in renal carcinomas. |
| Application Dilution |
| WB |
1:300-5000 |
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