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GluR1 + GluR2 Polyclonal Antibody, AbBy Fluor® 750 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Horse
Overview
Catalog # bs-10042r-bf750-100ul
Product Name GluR1 + GluR2 Polyclonal Antibody, AbBy Fluor® 750 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Specificity Due to the similarity of this protein to GluR2, there is a chance that this antibody will react with this protein based on homology.
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Cow, Horse
Specifications
Conjugation AbBy Fluor® 750
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GluR1
Immunogen Range 141-240/906
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2890
Swiss Prot P42261
Subcellular location Cytoplasm, Cell membrane
Synonyms GLUH1; GLUR1; GLURA; GluA1; HBGR1; Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GRIA1
Background Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200