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ChRM2 Polyclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
  • Dog
  • Cow
  • Pig
  • Chicken
Overview
Catalog # bs-0441R-PE
Product Name ChRM2 Polyclonal Antibody, PE Conjugated
Applications WB, FCM
Reactivity Human, Rat
Predicted Reactivity Mouse, Dog, Cow, Pig, Chicken
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ChRM2
Immunogen Range 168-250/466
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 1129
Swiss Prot P08172
Subcellular location Cell membrane
Synonyms HM2; Muscarinic acetylcholine receptor M2; CHRM2
Background The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
Application Dilution
WB 1:300-5000
FCM 1:20-100