Recombinant mouse IL-1b protein, C-His

Overview
Catalog #	bs-41073P
Product Name	Recombinant mouse IL-1b protein, C-His
Applications	ELISA
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant mouse IL-1b protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 117-269/269.
Storage Buffer	0.01M TBS(pH7.4)
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	16176
Swiss Prot	P10749
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].