Recombinant human TNF alpha protein, GST

Overview
Catalog #	bs-2258P
Product Name	Recombinant human TNF alpha protein, GST
Applications	ELISA
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human TNF alpha protein, GST protein is expressed in E.coli with GST. It contains the amino acid sequence of 77-233/233.
Storage Buffer	0.01M TBS(pH7.4)
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	7124
Swiss Prot	P01375
Background	This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]