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ABCB1 Monoclonal Antibody + Cell Lysate Kit

Applications

  • WB
  • IC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-90000R
Product Name ABCB1 Monoclonal Antibody + Cell Lysate Kit
Applications WB, IC
Specificity Knockdown Validated
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source A synthesized peptide derived from human P Glycoprotein
Immunogen Range 350-750/1280
Clonality Monoclonal
Clone # 23GB1330
Isotype IgG
Concentration Lot dependent
Purification Affinity Purified
Storage Buffer Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Storage Condition -20 °C
Target
Gene ID 5243
Swiss Prot P08183
Synonyms ABCB1; ATP Binding Cassette Subfamily B Member 1; PGY1; Multidrug Resistance Protein 1; CD243; GP170; ABC20; P-170; MDR1; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1; ATP-Dependent Translocase ABCB1; Phospholipid Transporter ABCB1; Colchicin Sensitivity; P-Glycoprotein 1; CLCS; P-GP; ATP-Binding Cassette Sub-Family B Member 1; Doxorubicin Resistance; P-Glycoprotein; CD243 Antigen; EC 3.6.3.44; EC 7.6.2.2; EC 7.6.2.1; EC 3.6.3; P-Gp
Background Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells

Cell Line: HeLa

Knockdown technology: shRNA Knockdown
Application Dilution
WB : 1:1000-1:5000
IC IC: 1:1000