CD2 monoclonal Antibody
Applications
Predicted Reactivity
Overview | |
Catalog # | bsm-60313R |
Product Name | CD2 monoclonal Antibody |
Applications | IF, ICC |
Predicted Reactivity | Human |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human CD2 |
Clonality | Monoclonal |
Clone # | C11G5 |
Isotype | IgG |
Concentration | 1mg/ml |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 914 |
Swiss Prot | P06729 |
Subcellular location | Cell membrane |
Synonyms | T-cell surface antigen CD2; CD 2; CD2 antigen; CD2 molecule; LFA2; LFA3 receptor; Lymphocyte function antigen 2; p50; Rosette receptor; Sheep erythrocyte receptor; Sheep red blood cell receptor; SRBC; T cell surface antigen CD2; T cell surface antigen T11/Leu 5; T11; CD2_HUMAN. |
Background | CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin. |
Application Dilution | |
IF | ICC=1:50 |
ICC | IF=1:50 |