Overview |
bsm-58001R |
FRATAXIN (2G1) Monoclonal Antibody |
WB |
Human |
Specifications |
Unconjugated |
Rabbit |
Full length recombinant human Frataxin protein |
Monoclonal |
2G1 |
IgG |
Not Determined |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
2395 |
Q16595 |
Frataxin, mitochondrial; FXN; Friedreich ataxia protein; FRDA; X25 |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1. |
Application Dilution |
WB |
1:300-5000 |